Synonyms G-9165; ERAB; HADH2; MRPP2; SCHAD; XH98G2; type II HADH; short-chain type dehydrogenase/reductase XH98G2; mitochondrial RNase P protein 2; mitochondrial ribonuclease P protein 2; endoplasmic reticulum-associated amyloid beta-peptide-binding protein; 3-hydroxyacyl-CoA dehydrogenase type II; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 10
Accession IDs HS01071 (MetaCyc)
Q99714 (UniProt)
Q99714 (UniProt)		 Length 3114 bp / 1037 aa
Map Position
[51,162,492 <- 51,165,605] (33.76 centisomes)
Location mitochondrion
Reactions 1.1.1.35: a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+ ↔ a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+
1.1.1.178: NAD+ + (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA ↔ NADH + 2-methylacetoacetyl-CoA + H+
1.1.1.178: a short-chain (3S)-3-hydroxy-2-methylacyl-CoA + NAD+ → a short-chain 2-methyl-3-oxoacyl-CoA + NADH + H+
1.1.1.239: testosterone + NAD+ ↔ androstenedione + NADH + H+
Pathways valproate β-oxidation
glutaryl-CoA degradation
docosahexaenoate biosynthesis III (6-desaturase, mammals)
Evidence
Inferred from experiment
Assay of protein purified to homogeneity [Ofman03]
Assay of protein purified to homogeneity from a heterologous host [He99, He98]