Definition: A chokepoint reaction is a reaction that either uniquely consumes a specific reactant or uniquely produces a specific product in a metabolic network. The metabolite in question must be balanced by a producing or consuming reaction (in other words, the metabolite must not be a dead-end). The definition of a chokepoint used here was derived from: Genome Research 14:917 (2004) "Computational analysis of Plasmodium falciparum metabolism: Organizing genomic information to facilitate drug discovery". [Pubmed].
The definition of a chokepoint used here was derived from: Genome Research 14:917 (2004) "Computational analysis of Plasmodium falciparum metabolism: Organizing genomic information to facilitate drug discovery". [Pubmed].
hide
show operations