MetaCyc N-terminal methionine Nalpha-acetyltransferase NatE

MetaCyc N-terminal methionine Nalpha-acetyltransferase NatE Skip to main content

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enzyme

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Synonyms	MAK3; NAT5; NAT13; N-alpha-acetyltransferase 50; hNAT5; hSAN; N-acetyltransferase 5; N-acetyltransferase 13
Accession IDs	HS04505 (MetaCyc) Q9GZZ1 (UniProt)	Length	27257 bp
Accession IDs	HS04505 (MetaCyc) Q9GZZ1 (UniProt)	Map Position	[113,008,362 <- 113,035,618]
Reactions	2.3.1.309: acetyl-CoA + a [β-tubulin]-L-lysine → a [β-tubulin]-N⁶-acetyl-L-lysine + coenzyme A + H⁺ 2.3.1.258: acetyl-CoA + an N-terminal-L-methionyl-L-threonyl-[protein] → an N-terminal N^α-acetyl-L-methionyl-L-threonyl-[protein] + coenzyme A + H⁺ 2.3.1.258: acetyl-CoA + an N-terminal-L-methionyl-L-seryl-[protein] → an N-terminal N^α-acetyl-L-methionyl-L-seryl-[protein] + coenzyme A + H⁺ + 6 more 2.3.1.258: acetyl-CoA + an N-terminal-L-methionyl-L-alanyl-[protein] → an N-terminal-N^α-acetyl-L-methionyl-L-alanyl-[protein] + coenzyme A + H⁺ 2.3.1.258: acetyl-CoA + an N-terminal-L-methionyl-L-valyl-[protein] → an N-terminal N^α-acetyl-L-methionyl-L-valyl-[protein] + coenzyme A + H⁺ 2.3.1.258: acetyl-CoA + an N-terminal L-methionyl-L-lysyl-[protein] → an N-terminal N^α-acetyl-L-methionyl-L-lysyl-[protein] + coenzyme A + H⁺ 2.3.1.256/2.3.1.258: acetyl-CoA + an N-terminal-L-methionyl-L-phenylalanyl-[protein] → an N-terminal N^α-acetyl-L-methionyl-L-phenylalanyl-[protein] + coenzyme A + H⁺ 2.3.1.256/2.3.1.258: acetyl-CoA + an N-terminal-L-methionyl-L-tyrosyl-[protein] → an N-terminal N^α-acetyl-L-methionyl-L-tyrosyl-[protein] + coenzyme A + H⁺ 2.3.1.256/2.3.1.258: acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[protein] → an N-terminal N^α-acetyl-L-methionyl-L-leucyl-[protein] + coenzyme A + H⁺ [Show fewer]
Pathway	Ac/N-end rule pathway
Evidence	Assay of unpurified protein expressed in a heterologous host [Van15] Inferred from genetic interaction [Chu11]

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Page generated by Pathway Tools version 28.5 (software by SRI International) on Tue Apr 1, 2025, BIOCYC13A.
MetaCyc version 28.5.