|
gene
aceF |
enzyme
pyruvate dehydrogenase E2 subunit |
|
| Escherichia coli K-12 substr. MG1655 |
| |
| Synonym | dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | ||
|---|---|---|---|
| Accession IDs |
EG10025 (MetaCyc) b0115 ECK0114 P06959 (UniProt) |
Length | 1893 bp / 630 aa |
| Map Position |
[125,695 -> 127,587]
| ||
| Location |
cytosol    | ||
| Reactions |
1.2.1.104: pyruvate + coenzyme A + NAD+ → acetyl-CoA + CO2 + NADH (catalyzed by complex) 2.3.1.12: acetyl-CoA + a [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine ← coenzyme A + a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine | ||
| Pathways |
photosynthetic 3-hydroxybutanoate biosynthesis (engineered) superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass pyruvate decarboxylation to acetyl CoA I | ||
| Evidence |
Inferred from mutant phenotype [Russell92]
| ||
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