Parent Class:

EC-Numbers → 7 -- Translocases → 7.5 -- Catalysing the translocation carbohydrates and their derivatives → 7.5.2 -- Linked to the hydrolysis of a nucleoside triphosphate

Synonyms: L-arabinose transporting ATPase, AraFGH, L-arabinose ABC transporter

Systematic Name: ATP phosphohydrolase (ABC-type, L-arabinose-importing)

Unification Links: BRENDA:7.5.2.12, ENZYME:7.5.2.12, IUBMB-ExplorEnz:7.5.2.12

Supersedes EC number: 3.6.3.17

Reaction:
ATP + L-arabinose_[periplasm] + H₂O → ADP + L-arabinose_[cytosol] + phosphate + H⁺

Enzymes and Genes:
arabinose ABC transporter: araF, araH, araG ( Escherichia coli K-12 substr. MG1655 )

Summary:
ABC-type (ATP-binding cassette-type) transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme which interacts with an extracytoplasmic substrate binding protein and mediates the high-affinity uptake of L-arabinose

Citations: [Scripture87, Horazdovsky89]

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References

Horazdovsky89: Horazdovsky BF, Hogg RW (1989). "Genetic reconstitution of the high-affinity L-arabinose transport system." J Bacteriol 171(6);3053-9. PMID: 2656640

Scripture87: Scripture JB, Voelker C, Miller S, O'Donnell RT, Polgar L, Rade J, Horazdovsky BF, Hogg RW (1987). "High-affinity L-arabinose transport operon. Nucleotide sequence and analysis of gene products." J Mol Biol 197(1);37-46. PMID: 2445996

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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