Parent Class:

EC-Numbers → 5 -- Isomerases → 5.4 -- Intramolecular transferases (mutases) → 5.4.1 -- Transferring acyl groups

Synonyms: mesaconyl-CoA C₁-C₄ CoA transferase, Mct

Systematic Name: 2-methylfumaryl-CoA 1,4-CoA-mutase

Unification Links: BRENDA:5.4.1.3, ENZYME:5.4.1.3, IUBMB-ExplorEnz:5.4.1.3

Reaction:
2-methylfumaryl-CoA ↔ 3-methylfumaryl-CoA

Enzymes and Genes:
mesaconyl-C1-CoA-C4-CoA transferase: mct ( Chloroflexus aurantiacus )

Summary:
The enzyme, purified from the bacterium Chloroflexus aurantiacus, acts as an intramolecular CoA transferase and does not transfer CoA to free mesaconate. It is part of the 3-hydroxypropanoate cycle for carbon assimilation.

Citations: [Zarzycki09]

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References

Zarzycki09: Zarzycki J, Brecht V, Muller M, Fuchs G (2009). "Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus." Proc Natl Acad Sci U S A 106(50);21317-22. PMID: 19955419

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Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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