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| Parent Class: | EC-Numbers → 2 -- Transferases → 2.8 -- Transferring sulfur-containing groups → 2.8.3 -- CoA-transferases |
Synonyms: aarC (gene name), SCACT
Systematic Name: succinyl-CoA:acetate CoA-transferase
Unification Links: BRENDA:2.8.3.18, ENZYME:2.8.3.18, IUBMB-ExplorEnz:2.8.3.18
Reaction:
succinyl-CoA + acetate ↔ succinate + acetyl-CoA
Enzymes and Genes:
succinyl-CoA:acetate CoA-transferase:
ASCT (
Fasciola hepatica
)
succinyl-CoA:acetate CoA-transferase:
aarC (
Acetobacter aceti
)
succinyl-CoA:CoA transferase:
cat1 (
Clostridium kluyveri
)
acetyl:succinate CoA-transferase (
Tritrichomonas suis
)
acetyl:succinate CoA-transferase:
ASCT (
Trypanosoma brucei
)
succinyl-CoA:acetate CoA-transferase:
aarC (
Cutibacterium granulosum
)
Summary:
In some bacteria the enzyme catalyses the conversion of acetate to acetyl-CoA as part of a modified tricarboxylic acid (TCA) cycle
[Mullins08,
Mullins12,
Kwong17]. In other organisms it converts acetyl-CoA to acetate during fermentation
[Steinbuchel86,
Sohling96,
vanGrinsven09,
Zhang21]. In some organisms the enzyme also catalyses the activity of
EC 2.8.3.27, propanoyl-CoA:succinate CoA transferase.
References
Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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