Parent Class:

EC-Numbers → 1 -- Oxidoreductases → 1.3 -- Acting on the CH-CH group of donors → 1.3.8 -- With a flavin as acceptor

Synonyms: cyclohexane-1-carbonyl-CoA dehydrogenase (ambiguous), aliB (gene name)

Systematic Name: cyclohexane-1-carbonyl-CoA:electron transfer flavoprotein oxidoreductase

Unification Links: BRENDA:1.3.8.11, ENZYME:1.3.8.11, IUBMB-ExplorEnz:1.3.8.11

Reaction:
cyclohexane-1-carbonyl-CoA + oxidized electron-transfer flavoprotein + H⁺ ↔ cyclohex-1-ene-1-carbonyl-CoA + reduced electron-transfer flavoprotein

Enzymes and Genes:
cyclohexane-1-carbonyl-CoA dehydrogenase: SYN_02586 ( Syntrophus aciditrophicus )
cyclohexanecarboxyl-CoA dehydrogenase: aliB ( Rhodopseudomonas palustris )
cyclohexane-1-carbonyl-CoA dehydrogenase: Gmet_3307 ( Geobacter metallireducens )

Summary:
The enzyme, characterized from the strict anaerobic bacterium Syntrophus aciditrophicus, is involved in production of cyclohexane-1-carboxylate, a byproduct produced by that organism during fermentation of benzoate and crotonate to acetate.

Citations: [Pelletier00, Kung13]

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References

Kung13: Kung JW, Seifert J, von Bergen M, Boll M (2013). "Cyclohexanecarboxyl-coenzyme A (CoA) and cyclohex-1-ene-1-carboxyl-CoA dehydrogenases, two enzymes involved in the fermentation of benzoate and crotonate in Syntrophus aciditrophicus." J Bacteriol 195(14);3193-200. PMID: 23667239

Pelletier00: Pelletier DA, Harwood CS (2000). "2-Hydroxycyclohexanecarboxyl coenzyme A dehydrogenase, an enzyme characteristic of the anaerobic benzoate degradation pathway used by Rhodopseudomonas palustris." J Bacteriol 2000;182(10);2753-60. PMID: 10781543

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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