ATCC 8483
for which no corresponding enzyme has been identified in the genome.
The presence of those enzymes is suggested by the presence of the
pathway.
101 pathway holes (18.6%) are present in the 542 total reactions of 175 pathways
|
Reaction |
EC# |
Pathway(s) needing this reaction |
|
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA ← a (2E)-2-enoyl-CoA + H2O |
4.2.1.17 |
fatty acid beta-oxidation I |
|
a (3Z)-3-enoyl-CoA → a (2E)-2-enoyl-CoA |
5.3.3.8 |
fatty acid beta-oxidation I |
|
a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA ↔ a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA |
5.1.2.3 |
fatty acid beta-oxidation I |
|
a 2,3,4-saturated fatty acyl CoA + acetyl-CoA ← a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A |
2.3.1.16 |
fatty acid beta-oxidation I |
|
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+ → a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+ |
1.1.1.35 |
fatty acid beta-oxidation I |
|
D-erythrose 4-phosphate + NAD+ + H2O → 4-phospho-D-erythronate + NADH + 2 H+ |
1.2.1.72 |
pyridoxal 5'-phosphate biosynthesis I |
|
acetaldehyde + coenzyme A + NAD+ → acetyl-CoA + NADH + H+ |
1.2.1.10 |
2'-deoxy-alpha-D-ribose 1-phosphate degradation,
2-aminoethylphosphonate degradation I |
|
2-deoxy-α-D-ribose 1-phosphate → 2-deoxy-D-ribose 5-phosphate |
5.4.2.7 |
2'-deoxy-alpha-D-ribose 1-phosphate degradation |
|
2'-deoxycytidine + a nucleoside triphosphate → dCMP + a nucleoside diphosphate + H+ |
2.7.1.74 |
pyrimidine deoxyribonucleosides salvage |
|
[ThiS sulfur-carrier protein] + ATP + H+ → carboxy-adenylated-[ThiS sulfur-carrier protein] + diphosphate |
2.7.7.73 |
thiazole biosynthesis I (facultative anaerobic bacteria) |
|
[ThiI sulfur-carrier protein]-S-sulfanyl-L-cysteine + carboxy-adenylated-[ThiS sulfur-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster → thiocarboxy-[ThiS-Protein] + [ThiI sulfur-carrier protein]-L-cysteine + AMP + 2 oxidized ferredoxin [iron-sulfur] cluster |
2.8.1.- |
thiazole biosynthesis I (facultative anaerobic bacteria) |
|
oxidized thioredoxin + reduced two electron carrier ← reduced thioredoxin + oxidized electron carrier |
[none] |
thioredoxin pathway |
|
UDP-α-D-glucose + α-D-galactose 1-phosphate → UDP-α-D-galactose + α-D-glucopyranose 1-phosphate |
2.7.7.12 |
D-galactose degradation I (Leloir pathway) |
|
1,4-dihydroxy-2-naphthoyl-CoA + H2O → 2-carboxy-1,4-naphthoquinol + coenzyme A + H+ |
3.1.2.28 |
2-carboxy-1,4-naphthoquinol biosynthesis |
|
2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate → (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate |
4.2.99.20 |
2-carboxy-1,4-naphthoquinol biosynthesis |
|
palmitoyl-[acp] + NAD+ ← (2E)-hexadec-2-enoyl-[acp] + NADH + H+ |
1.3.1.9 |
palmitate biosynthesis II (bacteria and plants) |
|
myristoyl-[acp] + NAD+ ← (2E)-tetradec-2-enoyl-[acp] + NADH + H+ |
1.3.1.9 |
palmitate biosynthesis II (bacteria and plants) |
|
dodecanoyl-[acp] + NAD+ ← (2E)-dodec-2-enoyl-[acp] + NADH + H+ |
1.3.1.9 |
palmitate biosynthesis II (bacteria and plants) |
|
decanoyl-[acp] + NAD+ ← (2E)-dec-2-enoyl-[acp] + NADH + H+ |
1.3.1.9 |
palmitate biosynthesis II (bacteria and plants) |
|
octanoyl-[acp] + NAD+ ← (2E)-oct-2-enoyl-[acp] + NADH + H+ |
1.3.1.9 |
palmitate biosynthesis II (bacteria and plants) |
|
hexanoyl-[acp] + NAD+ ← (2E)-hex-2-enoyl-[acp] + NADH + H+ |
1.3.1.9 |
palmitate biosynthesis II (bacteria and plants) |
|
butanoyl-[acp] + NAD+ ← (2E)-but-2-enoyl-[acp] + NADH + H+ |
1.3.1.9 |
palmitate biosynthesis II (bacteria and plants) |
|
4-deoxy-2-O-sulfo-β-L-erythro-hex-4-enopyranuronosyl-(1,4)-D-N-sulfoglucosamine 6-O-sulfate + H2O → 4-deoxy-β-L-erythro-hex-4-enopyranuronosyl-(1,4)-D-N-sulfoglucosamine 6-O-sulfate + sulfate + H+ |
3.1.6.13 |
heparin degradation |
|
N,6-O-disulfo-D-glucosamine + H2O → N-sulfo-D-glucosamine + sulfate + H+ |
3.1.6.11 |
heparin degradation |
|
N-sulfo-D-glucosamine + H2O → D-glucosamine + sulfate |
3.10.1.1 |
heparin degradation |
|
S-ribosyl-L-homocysteine → L-homocysteine + autoinducer 2 |
4.4.1.21 |
S-adenosyl-L-methionine cycle I |
|
2'-deoxyadenosine + H+ + H2O → ammonium + 2'-deoxyinosine |
3.5.4.4 |
purine deoxyribonucleosides degradation I |
|
pppGpp + H2O → ppGpp + phosphate + H+ |
3.6.1.40 |
ppGpp biosynthesis |
|
a chitodextrin + n H2O → n N,N'-diacetylchitobiose + N,N',N''-triacetylchitotriose |
3.2.1.202 |
chitin degradation II (Vibrio) |
|
chitin + H2O → 2 a chitodextrin |
3.2.1.14 |
chitin degradation II (Vibrio) |
|
α-D-galacturonosy-(1→4)-α-D-galacturonate → D-galactopyranuronate + 4-deoxy-L-threo-hex-4-enopyranuronate |
4.2.2.- |
pectin degradation I |
|
UDP-N-acetyl-α-D-muramate + L-alanyl-γ-D-glutamyl-meso-diaminopimelate + ATP → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+ |
6.3.2.45 |
anhydromuropeptides recycling I |
|
GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala + H2O → N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate + L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine |
3.5.1.28 |
anhydromuropeptides recycling I |
|
1,6-anhydro-N-acetyl-β-muramate + ATP + H2O → N-acetyl-D-muramate 6-phosphate + ADP + H+ |
2.7.1.170 |
anhydromuropeptides recycling I |
|
a 5-methyltetrahydrofolate + 2 oxidized ferredoxin [iron-sulfur] cluster ← a 5,10-methylenetetrahydrofolate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ |
1.5.7.1 |
folate transformations I |
|
a tetrahydrofolate + trimethyl sulfonium ← dimethyl sulfide + a 5-methyltetrahydrofolate + H+ |
2.1.1.19 |
folate transformations I |
|
dADP + oxidized thioredoxin + H2O ← ADP + reduced thioredoxin |
1.17.4.1 |
adenosine deoxyribonucleotides de novo biosynthesis |
|
(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate → 7,8-dihydropteroate + diphosphate |
2.5.1.15 |
tetrahydrofolate biosynthesis |
|
guanine + H+ + H2O → xanthine + ammonium |
3.5.4.3 |
guanosine nucleotides degradation III |
|
L-glutamate + acetyl-CoA → N-acetyl-L-glutamate + coenzyme A + H+ |
2.3.1.1 |
L-ornithine biosynthesis I |
|
an (S-diacyl-sn-glyceryl)-L-cysteinyl-[apolipoprotein] + a phosphoglyceride → an N-acyl-(S-diacyl-sn-glyceryl)-L-cysteinyl-[lipoprotein] + a 1-lysophospholipid + H+ |
2.3.1.ck |
lipoprotein posttranslational modification |
|
a queuosine in tRNA + oxidized electron carrier + H2O ← an epoxyqueuosine34 in tRNA + reduced two electron carrier |
1.17.99.6 |
queuosine biosynthesis |
|
L-ribulose + ATP → L-ribulose 5-phosphate + ADP + H+ |
2.7.1.16 |
L-arabinose degradation I |
|
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O → 3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate |
2.5.1.54 |
3-dehydroquinate biosynthesis I |
|
stearoyl-[acp] + NAD+ ← (2E)-octadec-2-enoyl-[acp] + NADH + H+ |
1.3.1.9 |
stearate biosynthesis II (bacteria and plants) |
|
xanthine + NAD+ + H2O → urate + NADH + H+ |
1.17.1.4 |
guanosine nucleotides degradation III,
inosine 5'-phosphate degradation |
|
D-glucosamine 1-phosphate + acetyl-CoA → N-acetyl-α-D-glucosamine 1-phosphate + coenzyme A + H+ |
2.3.1.157 |
UDP-N-acetyl-D-glucosamine biosynthesis I,
anhydromuropeptides recycling I |
|
N-acetyl-α-D-glucosamine 1-phosphate + UTP + H+ → UDP-N-acetyl-α-D-glucosamine + diphosphate |
2.7.7.23 |
UDP-N-acetyl-D-glucosamine biosynthesis I,
anhydromuropeptides recycling I |
|
(R)-pantoate + NADP+ ← 2-dehydropantoate + NADPH + H+ |
1.1.1.169 |
phosphopantothenate biosynthesis I |
|
D-mannonate + NAD+ ← D-fructuronate + NADH + H+ |
1.1.1.57 |
D-fructuronate degradation |
|
(7Z)-tetradec-7-enoyl-[acp] + NAD+ ← (2E,7Z)-tetradeca-2,7-dienoyl-[acp] + NADH + H+ |
1.3.1.9 |
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) |
|
palmitoleoyl-[acp] + NAD+ ← (2E,9Z)-hexadeca-2,9-dienoyl-[acp] + NADH + H+ |
1.3.1.9 |
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) |
|
an N10-formyltetrahydrofolate + N1-(5-phospho-β-D-ribosyl)glycinamide → a tetrahydrofolate + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + H+ |
2.1.2.2 |
5-aminoimidazole ribonucleotide biosynthesis I |
|
dGDP + oxidized thioredoxin + H2O ← GDP + reduced thioredoxin |
1.17.4.1 |
guanosine deoxyribonucleotides de novo biosynthesis I |
|
sarcosine + oxygen + H2O → glycine + formaldehyde + hydrogen peroxide |
1.5.3.1 |
creatinine degradation I |
|
sarcosine + oxidized electron-transfer flavoprotein + H2O + H+ → glycine + formaldehyde + reduced electron-transfer flavoprotein |
1.5.8.3 |
creatinine degradation I |
|
creatine + H2O → urea + sarcosine |
3.5.3.3 |
creatinine degradation I |
|
α-D-ribose-1-phosphate → D-ribose 5-phosphate |
5.4.2.7 |
purine ribonucleosides degradation |
|
adenosine + H2O + H+ → inosine + ammonium |
3.5.4.4 |
purine ribonucleosides degradation |
|
L-homoserine + ATP → O-phospho-L-homoserine + ADP + H+ |
2.7.1.39 |
L-threonine biosynthesis |
|
2-methylbutanoyl-CoA + oxidized electron-transfer flavoprotein + H+ → (E)-2-methylcrotonoyl-CoA + reduced electron-transfer flavoprotein |
1.3.8.5 |
L-isoleucine degradation I |
|
2-methylacetoacetyl-CoA + coenzyme A ↔ propanoyl-CoA + acetyl-CoA |
2.3.1.9 |
L-isoleucine degradation I |
|
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA ← (E)-2-methylcrotonoyl-CoA + H2O |
4.2.1.17 |
L-isoleucine degradation I |
|
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD+ → 2-methylacetoacetyl-CoA + NADH + H+ |
1.1.1.178 |
L-isoleucine degradation I |
|
L-threonine → (2Z)-2-aminobut-2-enoate + H2O + H+ |
[none] |
L-isoleucine biosynthesis I (from threonine) |
|
an acyl-CoA + sn-glycerol 3-phosphate → a 2-lysophosphatidate + coenzyme A |
2.3.1.15 |
CDP-diacylglycerol biosynthesis I |
|
demethylated methyl acceptor + S-adenosyl-L-methionine ↔ S-adenosyl-L-homocysteine + methylated methyl acceptor + H+ |
2.1.1.- |
S-adenosyl-L-methionine cycle I,
S-adenosyl-L-methionine cycle II,
L-methionine degradation I (to L-homocysteine) |
|
glycolaldehyde + NAD+ + H2O → glycolate + NADH + 2 H+ |
1.2.1.21 |
D-arabinose degradation I |
|
D-ribulose 1-phosphate → glycolaldehyde + glycerone phosphate |
[none] |
D-arabinose degradation I |
|
D-ribulose + ATP → D-ribulose 1-phosphate + ADP + H+ |
[none] |
D-arabinose degradation I |
|
(2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate → di-trans,octa-cis-undecaprenyl diphosphate + 8 diphosphate |
2.5.1.31 |
di-trans,poly-cis-undecaprenyl phosphate biosynthesis |
|
(cis)-gondoyl-[acp] + NAD+ ← (2E,11Z)-icosa-2,11-dienoyl-[acp] + NADH + H+ |
1.3.1.9 |
gondoate biosynthesis (anaerobic) |
|
(S)-malate + NADP+ → CO2 + pyruvate + NADPH |
1.1.1.40 |
gluconeogenesis I |
|
guanosine + H2O → D-ribofuranose + guanine |
3.2.2.1 |
guanine and guanosine salvage II |
|
(S)-3-methyl-2-oxopentanoate + coenzyme A + 2 oxidized ferredoxin [iron-sulfur] cluster ↔ 2-methylbutanoyl-CoA + CO2 + 2 reduced ferredoxin [iron-sulfur] cluster + H+ |
1.2.7.7 |
L-isoleucine biosynthesis V |
|
dermatan sulfate(n) → dermatan sulfate(n-1) + 4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate |
4.2.2.21 |
dermatan sulfate degradation I (bacterial) |
|
4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate + H2O → 4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + sulfate + H+ |
3.1.6.9 |
dermatan sulfate degradation I (bacterial) |
|
glycine + a tetrahydrofolate + NAD+ → a 5,10-methylenetetrahydrofolate + ammonium + CO2 + NADH |
[none] |
N10-formyl-tetrahydrofolate biosynthesis,
folate transformations I |
|
[chaperone-ADP]-[disordered-form scaffold protein] complex + ATP → [Fe-S cluster biosynthesis chaperone]-ATP + [disordered-form [Fe-S] cluster scaffold protein] + ADP |
3.6.4.- |
[2Fe-2S] iron-sulfur cluster biosynthesis |
|
[chaperone-ATP]-[co-chaperone]-[scaffold protein-(2Fe-2S)] complex + apo-iron-sulfur protein → [chaperone-ADP]-[disordered-form scaffold protein] complex + [Fe-S cluster biosynthesis co-chaperone] + holo-[2Fe-2S] cluster protein + phosphate |
[none] |
[2Fe-2S] iron-sulfur cluster biosynthesis |
|
[co-chaperone]-[scaffold protein-(2Fe-2S)] complex + [Fe-S cluster biosynthesis chaperone]-ATP → [chaperone-ATP]-[co-chaperone]-[scaffold protein-(2Fe-2S)] complex |
[none] |
[2Fe-2S] iron-sulfur cluster biosynthesis |
|
[cysteine desulfurase]-[scaffold protein-(2Fe-2S)] complex + [Fe-S cluster biosynthesis co-chaperone] → [co-chaperone]-[scaffold protein-(2Fe-2S)] complex + [L-cysteine desulfurase] |
[none] |
[2Fe-2S] iron-sulfur cluster biosynthesis |
|
[cysteine desulfurase]-(S-sulfanyl)2-[disordered-form scaffold protein] complex + 2 Fe3+ → [cysteine desulfurase]-[scaffold protein-(2Fe-2S)] complex |
[none] |
[2Fe-2S] iron-sulfur cluster biosynthesis |
|
S-sulfanyl-[cysteine desulfurase]-S-sulfanyl-[disordered-form scaffold protein] complex → [cysteine desulfurase]-(S-sulfanyl)2-[disordered-form scaffold protein] complex |
2.8.1.- |
[2Fe-2S] iron-sulfur cluster biosynthesis |
|
S-sulfanyl-[cysteine desulfurase]-[disordered-form scaffold protein] complex → [cysteine desulfurase]-S-sulfanyl-[disordered-form scaffold protein] complex |
2.8.1.- |
[2Fe-2S] iron-sulfur cluster biosynthesis |
|
[S-sulfanyl-L-cysteine desulfurase]2 + [disordered-form [Fe-S] cluster scaffold protein] → S-sulfanyl-[cysteine desulfurase]-[disordered-form scaffold protein] complex |
[none] |
[2Fe-2S] iron-sulfur cluster biosynthesis |
|
α-L-fucopyranose ← β-L-fucopyranose |
5.1.3.29 |
fucose degradation |
|
L-fuculose + ATP → L-fuculose 1-phosphate + ADP + H+ |
2.7.1.51 |
fucose degradation |
|
L-fuculose 1-phosphate → (S)-lactaldehyde + glycerone phosphate |
4.1.2.17 |
fucose degradation |
|
7,8-dihydroneopterin 3'-triphosphate + H2O → 7,8-dihydroneopterin 3'-phosphate + diphosphate + H+ |
3.6.1.67 |
6-hydroxymethyl-dihydropterin diphosphate biosynthesis I |
|
7,8-dihydroneopterin 3'-phosphate + H2O → 7,8-dihydroneopterin + phosphate |
3.6.1.- |
6-hydroxymethyl-dihydropterin diphosphate biosynthesis I |
|
(1,4-α-D-galacturonosyl)(n+1) + H2O → (1,4-α-D-galacturonosyl)(n) + D-galactopyranuronate |
3.2.1.67 |
pectin degradation II |
|
D-tagaturonate → D-fructuronate |
5.1.2.7 |
pectin degradation II |
|
selenodiglutathione + NADPH + H+ → glutathioselenol + glutathione + NADP+ |
1.8.1.- |
selenate reduction |
|
hydrogen selenide + glutathione + NADP+ ← glutathioselenol + NADPH + H+ |
1.8.1.- |
selenate reduction |
|
selenite + AMP + glutathione disulfide + 3 H+ ← adenosine 5'-phosphoselenate + 2 glutathione |
1.8.4.9 |
selenate reduction |
|
gellan → n unsaturated gellan tetrasaccharide |
4.2.2.25 |
gellan degradation |
|
thiamine phosphate + H2O → thiamine + phosphate |
3.1.3.100 |
thiamine diphosphate biosynthesis III (Staphylococcus) |
|
2,3,4-saturated fatty acyl-[acp] + NAD+ ← trans-2-enoyl-[acyl-carrier protein] + NADH + H+ |
1.3.1.9 |
fatty acid elongation -- saturated |
|
nicotinamide + H2O → ammonium + nicotinate |
3.5.1.19 |
NAD salvage pathway I |
|
β-nicotinamide D-ribonucleotide + H2O → D-ribofuranose 5-phosphate + nicotinamide + H+ |
3.2.2.14 |
NAD salvage pathway I |
39 pathway holes have been filled by the pathway hole filler, in 175 pathways.
|
Hole-filler |
Hole EC# |
P(has-function) |
All functions of hole-filler |
Pathway(s) requiring this reaction |
|
RS00880 |
2.1.2.- |
0.924 |
formate-dependent phosphoribosylglycinamide formyltransferase |
superpathway of 5-aminoimidazole ribonucleotide biosynthesis,
5-aminoimidazole ribonucleotide biosynthesis II |
|
RS01400 |
2.7.1.17 |
0.983 |
carbohydrate kinase |
xylose degradation I |
|
tsaD |
2.3.1.234 |
0.998 |
tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD |
N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis |
|
RS02085 |
3.1.3.104 |
0.974 |
HAD family phosphatase |
flavin biosynthesis I (bacteria and plants) |
|
RS05915 |
6.3.5.1 |
0.999 |
NAD(+) synthase |
NAD biosynthesis I (from aspartate),
NAD salvage pathway I |
|
RS06515 |
1.1.1.103 |
0.948 |
UDP-glucose 4-epimerase |
L-threonine degradation II |
|
RS06555 |
3.6.1.31 |
1.000 |
bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE |
L-histidine biosynthesis |
|
RS07320 |
1.1.1.37 |
0.997 |
malate dehydrogenase |
gluconeogenesis I |
|
RS07605 |
2.3.1.41 |
0.996 |
beta-ketoacyl-[acyl-carrier-protein] synthase family protein |
stearate biosynthesis II (bacteria and plants) |
|
RS09010 |
1.1.1.38/1.1.1.39 |
0.940 |
NADP-dependent malic enzyme |
gluconeogenesis I |
|
zwf |
1.1.1.49 |
1.000 |
glucose-6-phosphate dehydrogenase |
pentose phosphate pathway (oxidative branch) I |
|
RS09600 |
3.1.3.11 |
0.956 |
fructose-bisphosphatase class III |
glycolysis I (from glucose 6-phosphate),
gluconeogenesis I |
|
RS13055 |
2.6.1.1 |
0.980 |
pyridoxal phosphate-dependent aminotransferase |
L-glutamate degradation II |
|
RS13065 |
2.3.1.31 |
0.971 |
homoserine O-succinyltransferase |
L-homocysteine biosynthesis |
|
RS13530 |
4.1.1.65 |
1.000 |
phosphatidylserine decarboxylase family protein |
phosphatidylethanolamine biosynthesis I |
|
RS14360 |
4.2.1.9 |
0.999 |
dihydroxy-acid dehydratase |
L-isoleucine biosynthesis IV,
L-isoleucine biosynthesis I (from threonine) |
|
RS14360 |
4.2.1.9 |
0.999 |
dihydroxy-acid dehydratase |
L-valine biosynthesis |
|
ilvC |
1.1.1.383 |
0.956 |
ketol-acid reductoisomerase |
L-isoleucine biosynthesis IV |
|
fabG |
1.3.1.10/1.3.1.39/1.3.1.104/2.3.1.85/2.3.1.86 |
0.928 |
3-oxoacyl-[acyl-carrier-protein] reductase |
fatty acid elongation -- saturated |
|
RS16525 |
4.1.3.27 |
1.000 |
anthranilate synthase component I |
L-tryptophan biosynthesis |
|
RS16750 |
2.7.1.45/2.7.1.178 |
0.936 |
sugar kinase |
D-fructuronate degradation,
D-galacturonate degradation I |
|
RS17645 |
2.6.1.52 |
1.000 |
3-phosphoserine/phosphohydroxythreonine transaminase |
L-serine biosynthesis |
|
gcvP |
2.1.2.10 |
1.000 |
glycine dehydrogenase (aminomethyl-transferring) |
glycine cleavage,
GCVMULTI-RXN |
|
RS18785 |
5.4.2.2 |
0.960 |
phospho-sugar mutase |
D-galactose degradation I (Leloir pathway) |
|
RS19030 |
1.5.1.15 |
0.983 |
bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase |
folate transformations I |
|
RS21025 |
3.1.7.2 |
1.000 |
bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase |
ppGpp biosynthesis |
|
RS21025 |
2.7.6.5 |
1.000 |
bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase |
ppGpp biosynthesis |
|
RS22040 |
2.3.1.129 |
1.000 |
acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase |
lipid IVA biosynthesis |
|
RS22045 |
4.2.1.59 |
0.993 |
bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/3-hydroxyacyl-ACP dehydratase |
gondoate biosynthesis (anaerobic) |
|
RS22045 |
4.2.1.59 |
0.993 |
bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/3-hydroxyacyl-ACP dehydratase |
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) |
|
RS22045 |
4.2.1.59 |
0.993 |
bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/3-hydroxyacyl-ACP dehydratase |
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) |
|
aroE |
1.1.1.282 |
0.989 |
shikimate 5-dehydrogenase |
chorismate biosynthesis from 3-dehydroquinate |
|
gap |
1.2.1.12 |
0.960 |
type I glyceraldehyde-3-phosphate dehydrogenase |
glycolysis I (from glucose 6-phosphate),
glycolysis III (from glucose),
gluconeogenesis I |
|
RS22260 |
6.3.5.2 |
0.995 |
glutamine-hydrolyzing GMP synthase |
guanosine ribonucleotides de novo biosynthesis |
|
RS22685 |
2.7.1.33 |
0.991 |
type III pantothenate kinase |
phosphopantothenate biosynthesis I |
|
RS22775 |
4.2.1.93 |
0.997 |
bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase |
NADH repair |
|
RS22960 |
4.3.99.3 |
0.999 |
radical SAM protein |
preQ0 biosynthesis |
|
RS23905 |
3.2.1.56 |
0.985 |
glucuronyl hydrolase |
heparin degradation |
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