Pathway Listing for Escherichia coli K-12 substr. W3110 Sorted by Pathway Score

Overview

This page presents some of the evidence used to determine which pathways are present in Escherichia coli K-12 substr. W3110. For each pathway, we show

• A diagram (the pathway evidence glyph) summarizing the presence of enzymes for each reaction in the pathway
• The normalized pathway score computed for the pathway
• The total number of reactions in the pathway
• The number of pathway reactions which an enzyme is present in Escherichia coli K-12 substr. W3110
• The number of those reactions that appear in other pathways in Escherichia coli K-12 substr. W3110 (and hence are not unique to the particular pathway)
• The number of reactions designated in MetaCyc as key indicators for the presence of this pathway, for which enzymes are present in Escherichia coli K-12 substr. W3110
• Whether this organism is within the taxonomic groups (if any) designated in MetaCyc as the taxonomic range of this pathway

Key to Pathway Evidence Glyph Edge Colors

	Enzyme present. An enzyme for this reaction has been identified in this organism
	Enzyme absent. An enzyme for this reaction has not been identified in this organism
	Unique reaction. This reaction is unique to this pathway in the MetaCyc database
	Enzyme present by hole filler. An enzyme for this reaction has been identified in this organism by the Pathway Hole Filler
	Orphan reaction. No sequenced enzyme from any domain of life is known for this reaction
	Key reaction. The reaction has been designated a key reaction of this pathway
	Spontaneous/other. Used for spontaneous reactions, and for lines that do not denote reactions (e.g., denoting repetition in polymerization pathways)

Pathway Summary Statistics

Fraction of genes devoted to metabolism	1541 of 4471 (34%)
Base pathways	281
Total reactions in the base pathways	871
Base pathway reactions that are pathway holes	49 (6%)
Base pathway reactions that are not pathway holes	822 (94%)

Pathways Sorted by Pathway Score

Pathway score is a number between 0 and 1 inclusive that indicates the likelihood that a pathway is present; a higher number indiciates a higher likelihood. The pathway score is not a probability. Pathway scores are computed at pathway prediction time and are not updated later, such as due to editing of a pathway.

A pathway might have no pathway score if its presence was inferred by a curator, or if it is a super-pathway (super-pathways are not scored, and are not included in this page).

Pathways with a score less than the prediction threshold (default=0.15) are typically not predicted as present. An exception to this rule is a case where MetaCyc contains experimental evidence that the pathway exists in the exact organism for which pathway inference was performed, in which case the pathway will be imported from MetaCyc no matter its score.

Pathway	Pathway Glyph	Pathway Score	Total Rxns	Rxns Present in Escherichia coli K-12 substr. W3110	Rxns Present in Other Pwys	Other Pwys	Key Rxns Present	In Taxonomic Range?	Links
3-phenylpropanoate and 3-(3-hydroxyphenyl)propanoate degradation to 2-oxopent-4-enoate		na	6	5	0	(none)	1 of 1	yes
D-galactarate degradation I		na	4	4	0	(none)	0 of 0	yes
anhydromuropeptides recycling		na	10	10	0	(none)	1 of 1	yes
methionine biosynthesis I		na	5	5	0	(none)	2 of 2	yes
dTDP-N-acetylthomosamine biosynthesis		na	4	4	0	(none)	0 of 0	yes
pentose phosphate pathway (non-oxidative branch)		na	5	5	0	(none)	1 of 1	yes
proline biosynthesis I		na	4	3	0	(none)	0 of 0	yes
cytidylyl molybdenum cofactor biosynthesis		na	1	1	0	(none)	0 of 0	yes
tryptophan biosynthesis		na	6	6	0	(none)	0 of 0	yes
D-malate degradation		na	1	1	0	(none)	0 of 0	yes
formylTHF biosynthesis		na	11	11	1	superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli)	0 of 0	yes
ubiquinol-8 biosynthesis (prokaryotic)		na	8	8	0	(none)	1 of 1	yes
thiosulfate disproportionation III (rhodanese)		na	1	1	0	(none)	0 of 0	yes
phenylalanine biosynthesis I		na	3	2	0	(none)	1 of 1	yes
thiazole biosynthesis I (E. coli)		na	7	7	0	(none)	0 of 0	yes
enterobacterial common antigen biosynthesis		na	5	3	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotides de novo biosynthesis I		na	9	8	8	superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli)	1 of 1	yes
CMP-KDO biosynthesis I		na	4	4	0	(none)	1 of 1	yes
tyrosine biosynthesis I		na	3	3	0	(none)	1 of 1	yes
hydrogen sulfide biosynthesis I		na	2	1	0	(none)	0 of 0	yes
cysteine biosynthesis I		na	2	2	0	(none)	0 of 0	yes
lipid IVA biosynthesis		na	6	6	0	(none)	0 of 0	yes
L-serine degradation		na	3	2	0	(none)	0 of 0	yes
D-serine degradation		na	1	1	0	(none)	0 of 0	yes
2-methylcitrate cycle I		na	5	5	0	(none)	1 of 1	yes
isoleucine biosynthesis I (from threonine)		na	7	6	0	(none)	1 of 1	yes
tryptophan degradation II (via pyruvate)		na	1	1	0	(none)	0 of 0	yes
2'-deoxy-alpha-D-ribose 1-phosphate degradation		na	3	3	1	mixed acid fermentation	0 of 0	yes
Lipid A-core biosynthesis		na	10	10	0	(none)	0 of 0	yes
L-lactaldehyde degradation (aerobic)		na	2	2	0	(none)	0 of 0	yes
guanosine nucleotides degradation III		na	4	4	0	(none)	0 of 0	yes
NADH to trimethylamine N-oxide electron transfer		na	2	2	0	(none)	2 of 2	yes
D-glucarate degradation I		na	4	4	0	(none)	0 of 0	yes
adenine and adenosine salvage II		na	2	2	0	(none)	0 of 0	yes
pyridoxal 5'-phosphate salvage I		na	5	5	0	(none)	0 of 0	yes
glycerol degradation I		na	2	2	0	(none)	0 of 0	yes
guanosine deoxyribonucleotides de novo biosynthesis II		na	4	4	0	(none)	2 of 2	yes
2,3-dihydroxybenzoate biosynthesis		na	3	2	0	(none)	0 of 0	yes
alanine biosynthesis I		na	3	3	0	(none)	0 of 0	yes
5-aminoimidazole ribonucleotide biosynthesis II		na	5	5	5	superpathway of 5-aminoimidazole ribonucleotide biosynthesis	0 of 0	yes
ethanolamine utilization		na	1	1	0	(none)	1 of 1	yes
S-adenosyl-L-methionine biosynthesis		na	1	1	0	(none)	0 of 0	yes
adenine and adenosine salvage V		na	3	3	0	(none)	2 of 2	yes
oleate beta-oxidation		na	3	3	0	(none)	0 of 0	yes
glutamate degradation II		na	2	2	0	(none)	0 of 0	yes
glucose and glucose-1-phosphate degradation		na	6	4	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotides de novo biosynthesis II		na	7	7	7	superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli)	2 of 2	yes
superoxide radicals degradation		na	2	2	0	(none)	0 of 0	yes
xanthine and xanthosine salvage		na	2	2	0	(none)	0 of 0	yes
fatty acid biosynthesis initiation III		na	2	2	1	superpathway of fatty acid biosynthesis initiation (E. coli)	0 of 0	yes
glutamate dependent acid resistance		na	1	1	0	(none)	0 of 0	yes
asparagine degradation I		na	1	1	1	superpathway of aspartate and asparagine biosynthesis; interconversion of aspartate and asparagine	0 of 0	yes
alanine degradation I		na	2	2	0	(none)	1 of 1	yes
adenosine nucleotides degradation III		na	1	1	0	(none)	0 of 0	yes
cyanate degradation		na	3	3	0	(none)	1 of 1	yes
tetrapyrrole biosynthesis I (from glutamate)		na	6	6	0	(none)	0 of 0	yes
Entner-Doudoroff pathway I		na	2	2	0	(none)	0 of 0	yes
spermidine biosynthesis I		na	2	1	0	(none)	0 of 0	yes
PRPP biosynthesis II		na	3	2	0	(none)	0 of 0	yes
ammonia assimilation cycle III		na	2	1	0	(none)	0 of 0	yes
phosphatidylethanolamine biosynthesis I		na	2	1	0	(none)	0 of 0	yes
ribose degradation		na	3	2	0	(none)	1 of 1	yes
trehalose degradation I (low osmolarity)		na	2	1	0	(none)	1 of 1	yes
fatty acid biosynthesis initiation II		na	2	2	2	superpathway of fatty acid biosynthesis initiation (E. coli)	0 of 0	yes
queuosine biosynthesis		na	4	4	0	(none)	0 of 0	yes
demethylmenaquinol-8 biosynthesis I		na	1	1	0	(none)	0 of 0	yes
uracil degradation III		na	6	5	0	(none)	0 of 0	yes
threonine degradation II		na	2	2	0	(none)	0 of 0	yes
trans, trans-farnesyl diphosphate biosynthesis		na	3	3	0	(none)	1 of 1	yes
leucine degradation I		na	6	2	0	(none)	0 of 1	yes
galactose degradation I (Leloir pathway)		na	5	5	1	colanic acid building blocks biosynthesis	0 of 0	yes
UTP and CTP de novo biosynthesis		na	3	3	0	(none)	0 of 0	yes
UDP-D-galactose biosynthesis		na	1	1	1	colanic acid building blocks biosynthesis	0 of 0	yes
NADH to fumarate electron transfer		na	2	2	1	mixed acid fermentation	2 of 2	yes
ornithine biosynthesis		na	5	5	0	(none)	1 of 1	yes
allantoin degradation to ureidoglycolate II (ammonia producing)		na	3	3	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleosides degradation		na	3	3	0	(none)	0 of 0	yes
xylose degradation I		na	2	2	0	(none)	0 of 0	yes
D-arabinose degradation I		na	4	4	0	(none)	1 of 1	yes
pyrimidine ribonucleosides salvage II		na	2	2	0	(none)	1 of 1	yes
acyl-CoA hydrolysis		na	1	1	0	(none)	0 of 0	yes
UMP biosynthesis		na	6	6	1	arginine biosynthesis I (via L-ornithine)	1 of 1	yes
arginine degradation II (AST pathway)		na	5	5	0	(none)	0 of 0	yes
serine biosynthesis		na	3	3	0	(none)	0 of 0	yes
guanine and guanosine salvage III		na	1	1	0	(none)	0 of 0	yes
UDP-glucose biosynthesis		na	3	2	0	(none)	0 of 0	yes
CDP-diacylglycerol biosynthesis I		na	4	4	0	(none)	0 of 0	yes
threonine degradation IV		na	2	2	1	mixed acid fermentation	0 of 0	yes
L-rhamnose degradation I		na	5	4	0	(none)	1 of 1	yes
NAD salvage pathway III		na	2	2	0	(none)	0 of 0	yes
threonine degradation III (to methylglyoxal)		na	3	2	0	(none)	1 of 1	yes
fatty acid beta-oxidation I		na	7	6	0	(none)	0 of 0	yes
acetate conversion to acetyl-CoA		na	1	1	0	(none)	0 of 0	yes
2-O-alpha-mannosyl-D-glycerate degradation		na	2	2	0	(none)	1 of 1	yes
4-aminobenzoate biosynthesis		na	2	2	0	(none)	0 of 0	yes
phenylacetate degradation I (aerobic)		na	9	8	0	(none)	0 of 0	yes
NAD salvage pathway I		na	7	4	0	(none)	0 of 0	yes
ADP-L-glycero-beta-D-manno-heptose biosynthesis		na	5	5	0	(none)	1 of 1	yes
cardiolipin biosynthesis III		na	3	3	0	(none)	1 of 1	yes
methylglyoxal degradation II		na	2	2	0	(none)	0 of 0	yes
NADH to cytochrome bd oxidase electron transfer		na	2	2	0	(none)	2 of 2	yes
adenosine deoxyribonucleotides de novo biosynthesis II		na	4	4	0	(none)	2 of 2	yes
TCA cycle I (prokaryotic)		na	10	10	6	mixed acid fermentation	1 of 1	yes
glycogen biosynthesis I (from ADP-D-Glucose)		na	5	4	0	(none)	1 of 1	yes
D-galactonate degradation		na	3	3	0	(none)	0 of 0	yes
L-ascorbate degradation II (bacterial, aerobic)		na	8	5	0	(none)	0 of 0	yes
D-mannose degradation		na	1	1	0	(none)	1 of 1	yes
lipoate biosynthesis and incorporation I		na	2	2	0	(none)	0 of 0	yes
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-DAP-containing)		na	8	8	0	(none)	2 of 2	yes
lipoate biosynthesis and incorporation II		na	2	2	0	(none)	1 of 1	yes
valine biosynthesis		na	4	4	0	(none)	0 of 0	yes
taurine degradation IV		na	1	1	0	(none)	0 of 0	yes
4-aminobutyrate degradation		na	2	2	0	(none)	0 of 0	yes
sedoheptulose bisphosphate bypass		na	2	2	0	(none)	1 of 1	yes
beta-alanine biosynthesis III		na	na	na	0	(none)	0 of 0	yes
leucine biosynthesis		na	6	5	0	(none)	0 of 0	yes
coenzyme A biosynthesis		na	4	4	0	(none)	1 of 1	yes
N-acetylneuraminate and N-acetylmannosamine degradation		na	3	2	0	(none)	0 of 0	yes
thioredoxin pathway		na	2	1	0	(none)	0 of 0	yes
5-aminoimidazole ribonucleotide biosynthesis I		na	5	5	4	superpathway of 5-aminoimidazole ribonucleotide biosynthesis	0 of 0	yes
lipoate salvage I		na	2	2	0	(none)	0 of 0	yes
preQ0 biosynthesis		na	4	4	0	(none)	0 of 0	yes
alanine biosynthesis II		na	1	1	0	(none)	0 of 0	yes
salvage pathways of pyrimidine ribonucleotides		na	8	8	0	(none)	0 of 0	yes
gluconeogenesis I		na	13	13	1	mixed acid fermentation	0 of 0	yes
heme biosynthesis from uroporphyrinogen-III II (anaerobic)		na	4	4	2	superpathway of heme biosynthesis from uroporphyrinogen-III	1 of 1	yes
cis-dodecenoyl biosynthesis		na	6	6	0	(none)	2 of 2	yes
nitrate reduction III (dissimilatory)		na	2	2	0	(none)	2 of 2	yes
PRPP biosynthesis I		na	1	1	0	(none)	0 of 0	yes
lysine degradation I		na	1	1	0	(none)	1 of 1	yes
methylerythritol phosphate pathway		na	9	6	0	(none)	1 of 1	yes
guanine and guanosine salvage		na	2	2	0	(none)	0 of 0	yes
formate to trimethylamine N-oxide electron transfer		na	2	2	0	(none)	2 of 2	yes
NADH to dimethyl sulfoxide electron transfer		na	2	2	0	(none)	2 of 2	yes
D-allose degradation		na	3	3	0	(none)	0 of 0	yes
beta-D-glucuronide and D-glucuronate degradation		na	3	2	0	(none)	0 of 0	yes
arsenate detoxification II (glutaredoxin)		na	1	1	0	(none)	1 of 2	NO
GDP-L-fucose biosynthesis I (from GDP-D-mannose)		na	2	2	0	(none)	0 of 2	yes
arginine degradation III (arginine decarboxylase/agmatinase pathway)		na	2	2	0	(none)	0 of 0	yes
D-galacturonate degradation I		na	4	4	0	(none)	0 of 0	yes
4-hydroxybenzoate biosynthesis II (bacteria and fungi)		na	1	1	0	(none)	0 of 0	yes
pyridoxal 5'-phosphate biosynthesis I		na	8	6	0	(none)	0 of 0	yes
menaquinol-8 biosynthesis		na	1	1	0	(none)	0 of 0	yes
4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis		na	2	2	0	(none)	0 of 0	yes
N-acetylglucosamine degradation I		na	2	2	0	(none)	0 of 0	yes
heme biosynthesis from uroporphyrinogen-III I (aerobic)		na	4	3	3	superpathway of heme biosynthesis from uroporphyrinogen-III	1 of 1	yes
chorismate biosynthesis from 3-dehydroquinate		na	6	5	0	(none)	0 of 0	yes
molybdenum cofactor biosynthesis		na	7	6	0	(none)	0 of 0	yes
fructose degradation		na	1	1	0	(none)	0 of 0	yes
dTDP-L-rhamnose biosynthesis I		na	4	4	0	(none)	1 of 1	yes
acyl carrier protein metabolism I		na	2	2	0	(none)	0 of 0	yes
acetoacetate degradation (to acetyl CoA)		na	2	2	0	(none)	1 of 1	yes
glycine biosynthesis I		na	1	1	0	(none)	0 of 0	yes
pyrimidine ribonucleosides degradation		na	2	2	0	(none)	1 of 1	yes
glycerol degradation V		na	2	2	0	(none)	0 of 0	yes
CDP-diacylglycerol biosynthesis II		na	4	4	0	(none)	0 of 0	yes
pseudouridine degradation		na	2	2	0	(none)	0 of 0	yes
6-hydroxymethyl-dihydropterin diphosphate biosynthesis I		na	5	4	0	(none)	1 of 1	yes
adenine and adenosine salvage III		na	4	4	0	(none)	2 of 2	yes
guanylyl molybdenum cofactor biosynthesis		na	1	1	0	(none)	0 of 0	yes
proline to cytochrome bo oxidase electron transfer		na	2	2	0	(none)	0 of 0	yes
salvage pathways of pyrimidine deoxyribonucleotides		na	5	5	0	(none)	0 of 0	yes
KDO transfer to lipid IVA I		na	2	2	0	(none)	0 of 0	yes
glycine betaine biosynthesis I (Gram-negative bacteria)		na	2	2	0	(none)	0 of 0	yes
1,4-dihydroxy-2-naphthoate biosynthesis I		na	7	7	0	(none)	1 of 1	yes
citrate lyase activation		na	5	3	0	(none)	0 of 0	yes
glutathione biosynthesis		na	2	2	0	(none)	0 of 0	yes
di-trans,poly-cis-undecaprenyl phosphate biosynthesis		na	1	1	0	(none)	0 of 0	yes
L-lactaldehyde degradation (anaerobic)		na	1	1	0	(none)	0 of 0	yes
chitobiose degradation		na	na	na	0	(none)	0 of 0	yes
asparagine biosynthesis I		na	1	1	0	(none)	0 of 0	yes
respiration (anaerobic)		na	13	13	12	superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass mixed acid fermentation	0 of 0	yes
curcumin degradation		na	2	2	0	(none)	0 of 0	yes
formate to dimethyl sulfoxide electron transfer		na	2	2	0	(none)	2 of 2	yes
siroheme biosynthesis		na	4	4	0	(none)	0 of 0	yes
glutathionylspermidine biosynthesis		na	1	1	0	(none)	0 of 0	yes
threonine biosynthesis from homoserine		na	2	2	0	(none)	0 of 0	yes
guanosine ribonucleotides de novo biosynthesis		na	4	4	0	(none)	0 of 0	yes
NAD biosynthesis I (from aspartate)		na	6	5	0	(none)	1 of 1	yes
L-lyxose degradation		na	4	4	0	(none)	1 of 1	yes
melibiose degradation		na	1	1	0	(none)	0 of 0	yes
UDP-N-acetyl-alpha-D-mannosaminouronate biosynthesis		na	2	2	0	(none)	0 of 0	yes
thiamin diphosphate biosynthesis I (E. coli)		na	2	2	0	(none)	0 of 0	yes
glycogen degradation I		na	7	7	0	(none)	1 of 1	yes
phenylethylamine degradation I		na	2	1	0	(none)	1 of 1	yes
glutamine biosynthesis I		na	1	1	0	(none)	0 of 0	yes
two-component alkanesulfonate monooxygenase		na	2	2	0	(none)	1 of 1	yes
purine ribonucleosides degradation		na	6	6	0	(none)	0 of 0	yes
adenosine nucleotides degradation II		na	5	5	0	(none)	1 of 1	yes
arginine dependent acid resistance		na	1	1	0	(none)	0 of 0	yes
cis-vaccenate biosynthesis		na	5	5	0	(none)	0 of 1	yes
homoserine biosynthesis		na	3	3	0	(none)	0 of 0	yes
palmitate biosynthesis II (bacteria and plants)		na	29	27	0	(none)	1 of 1	yes
glycolysis II (from fructose-6P)		na	10	10	1	mixed acid fermentation	0 of 0	yes
methylglyoxal degradation I		na	3	3	0	(none)	1 of 2	yes
conversion of succinate to propionate		na	3	3	0	(none)	0 of 0	yes
succinate to cytochrome bd oxidase electron transfer		na	2	2	0	(none)	2 of 2	yes
cardiolipin biosynthesis I		na	3	3	0	(none)	1 of 1	yes
alanine biosynthesis III		na	1	1	0	(none)	0 of 0	yes
succinate to cytochrome bo oxidase electron transfer		na	2	2	0	(none)	2 of 2	yes
L-arabinose degradation I		na	3	3	0	(none)	0 of 0	yes
glutamine degradation I		na	1	1	0	(none)	0 of 0	yes
aminopropylcadaverine biosynthesis		na	2	2	0	(none)	1 of 1	yes
NAD phosphorylation and dephosphorylation I		na	3	3	0	(none)	1 of 1	yes
glycolate and glyoxylate degradation II		na	2	2	0	(none)	0 of 0	yes
sulfate activation for sulfonation		na	2	2	0	(none)	0 of 0	yes
biotin biosynthesis from 8-amino-7-oxononanoate I		na	3	3	0	(none)	1 of 1	yes
tRNA processing pathway I		na	9	8	0	(none)	0 of 0	yes
glycerophosphodiester degradation		na	2	2	0	(none)	0 of 0	yes
putrescine biosynthesis I		na	2	2	0	(none)	0 of 0	yes
(KDO)2-lipid A biosynthesis I		na	2	2	2	superpathway of (KDO)2-lipid A biosynthesis	0 of 0	yes
fatty acid elongation -- saturated		na	5	5	0	(none)	0 of 0	yes
L-cysteine degradation II		na	3	2	0	(none)	1 of 1	yes
pyruvate oxidation pathway		na	1	1	0	(none)	0 of 0	yes
L-ascorbate degradation I (bacterial, anaerobic)		na	4	4	0	(none)	1 of 1	yes
folate polyglutamylation		na	5	4	0	(none)	0 of 0	yes
L-carnitine degradation I		na	4	4	0	(none)	0 of 0	yes
nitrate reduction VIII (dissimilatory)		na	2	2	0	(none)	2 of 2	yes
ethanol degradation I		na	2	2	2	mixed acid fermentation	1 of 1	yes
putrescine biosynthesis III		na	1	1	1	superpathway of ornithine degradation	0 of 0	yes
4-hydroxyphenylacetate degradation		na	8	1	0	(none)	0 of 1	yes
glutamate biosynthesis III		na	1	1	0	(none)	0 of 0	yes
UDP-N-acetyl-D-glucosamine biosynthesis I		na	5	5	0	(none)	0 of 0	yes
ethylene glycol degradation		na	2	2	0	(none)	0 of 0	yes
acetate formation from acetyl-CoA I		na	2	2	2	mixed acid fermentation	0 of 0	yes
aminopropanol phosphate biosynthesis I		na	na	na	0	(none)	0 of 1	yes
cinnamate and 3-hydroxycinnamate degradation to 2-oxopent-4-enoate		na	6	5	0	(none)	0 of 0	yes
lactose degradation III		na	1	1	0	(none)	0 of 0	yes
selenocysteine biosynthesis I (bacteria)		na	3	3	0	(none)	1 of 1	yes
UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)		na	1	1	0	(none)	0 of 0	yes
fatty acid biosynthesis initiation I		na	3	2	0	(none)	1 of 1	yes
glycolate and glyoxylate degradation I		na	4	3	0	(none)	1 of 1	yes
putrescine degradation I		na	2	2	0	(none)	0 of 0	yes
D-fructuronate degradation		na	4	4	0	(none)	0 of 0	yes
S-adenosyl-L-methionine cycle I		na	5	4	1	aspartate superpathway superpathway of S-adenosyl-L-methionine biosynthesis	2 of 2	yes
adenosylcobalamin salvage from cobalamin		na	1	1	0	(none)	0 of 0	yes
fucose degradation		na	4	4	0	(none)	1 of 1	yes
histidine biosynthesis		na	10	10	0	(none)	0 of 0	yes
fructoselysine and psicoselysine degradation		na	3	3	0	(none)	0 of 0	yes
threonine degradation I		na	6	5	0	(none)	0 of 0	yes
inosine-5'-phosphate biosynthesis I		na	6	6	0	(none)	3 of 3	yes
flavin biosynthesis I (bacteria and plants)		na	9	9	0	(none)	1 of 1	yes
L-idonate degradation		na	3	3	0	(none)	0 of 0	yes
tetrahydromonapterin biosynthesis		na	3	2	0	(none)	0 of 0	yes
4-aminobutyrate degradation II		na	2	2	0	(none)	0 of 0	yes
octaprenyl diphosphate biosynthesis		na	1	1	0	(none)	0 of 0	yes
trehalose biosynthesis I		na	2	2	0	(none)	1 of 1	yes
mannitol degradation I		na	1	1	0	(none)	0 of 0	yes
tetrahydrofolate biosynthesis		na	3	3	0	(none)	1 of 1	yes
cyclopropane fatty acid (CFA) biosynthesis		na	1	1	0	(none)	0 of 0	yes
pentose phosphate pathway (oxidative branch) I		na	4	3	2	superpathway of glycolysis and Entner-Doudoroff	0 of 0	yes
L-galactonate degradation		na	1	1	0	(none)	0 of 0	yes
palmitoleate biosynthesis I		na	9	9	0	(none)	3 of 3	yes
NADH to cytochrome bo oxidase electron transfer		na	2	2	0	(none)	2 of 2	yes
proline degradation		na	3	1	0	(none)	0 of 1	yes
adenosine ribonucleotides de novo biosynthesis		na	4	4	0	(none)	0 of 0	yes
sulfoglycolysis		na	4	4	0	(none)	1 of 1	yes
putrescine degradation II		na	4	4	0	(none)	1 of 1	yes
tRNA charging		na	20	20	0	(none)	0 of 0	yes
2-oxopentenoate degradation		na	3	3	1	mixed acid fermentation	0 of 0	yes
glutamate biosynthesis I		na	1	1	0	(none)	0 of 0	yes
polymyxin resistance		na	6	6	0	(none)	0 of 0	yes
trehalose degradation VI (periplasmic)		na	2	1	0	(none)	0 of 0	yes
pyruvate decarboxylation to acetyl CoA		na	3	3	0	(none)	1 of 1	yes
8-amino-7-oxononanoate biosynthesis I		na	11	11	0	(none)	2 of 2	yes
asparagine biosynthesis II		na	1	1	0	(none)	0 of 0	yes
phosphopantothenate biosynthesis I		na	4	4	0	(none)	0 of 0	yes
D-sorbitol degradation II		na	2	1	0	(none)	0 of 0	yes
glutathione redox reactions II		na	2	1	0	(none)	0 of 0	yes
aspartate biosynthesis		na	1	1	0	(none)	0 of 0	yes
D-gluconate degradation		na	1	1	0	(none)	0 of 0	yes
glyoxylate cycle		na	6	6	4	mixed acid fermentation	2 of 2	yes
trehalose degradation II (trehalase)		na	3	2	0	(none)	1 of 1	yes
formaldehyde oxidation II (glutathione-dependent)		na	3	2	0	(none)	1 of 1	yes
galactitol degradation		na	3	2	0	(none)	1 of 1	yes
lysine biosynthesis I		na	9	9	0	(none)	1 of 1	yes
3-dehydroquinate biosynthesis I		na	2	2	0	(none)	0 of 0	yes
glycolysis I (from glucose-6P)		na	11	11	1	mixed acid fermentation	0 of 0	yes
2-oxoglutarate decarboxylation to succinyl-CoA		na	3	3	0	(none)	1 of 1	yes
GDP-mannose biosynthesis		na	4	4	0	(none)	0 of 0	yes
methylglyoxal degradation III		na	2	2	0	(none)	0 of 0	yes

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