MetaCyc Metabolic Pathway Database
MetaCyc is a curated database of experimentally elucidated metabolic pathways from all domains of life. MetaCyc contains 2859 pathways from 3185 different organisms.
MetaCyc contains pathways involved in both primary and secondary metabolism, as well as associated metabolites, reactions, enzymes, and genes. The goal of MetaCyc is to catalog the universe of metabolism by storing a representative sample of each experimentally elucidated pathway.
MetaCyc applications include:
- Online encyclopedia of metabolism
- Predict metabolic pathways in sequenced genomes
- Support metabolic engineering via enzyme database
- Metabolite database aids metabolomics research
Ajmaline is an antiarrhythmic agent produced by the plant Rauvolfia serpentina. Why is it named after the Indian physician Hakim Ajmal Khan?Learn More
It is well known that vitamin D is produced in our skin during exposure to the sun. But did you know it is made from cholesterol?Learn More
Biological processes influence geochemical cycles. The main input of sulfur to the atmosphere is dimethyl sulfide, which is formed by microbial degradation of marine algae biomass.Learn More
So what killed this guy?Learn More
Twenty people were executed around Salem, MA for using witchcraft to afflict young girls. Were the victims bewitched, or could it be something they ate?Learn More
Have you ever swum in the ocean and started to itch? Care to know why?Learn More
Beer is the world's most widely consumed alcoholic drink, and, with evidence dating as far back as 5000 BCE, one of its oldest. Did the ancient Egyptians know all about bitter acids?Learn More
We all know about the A, B, and O blood types, but did you know that a single glycosyltransferase is responsible for all of this diversity?Learn More
Chitin is the second most common polymer in the world, after cellulose. Our understanding of its degradation was significantly boosted with the discovery of LPMOs. And what are LPMOs?Learn More
When oil companies started adding MTBE to gasoline, it seemed like a good idea. Now it is banned in the US, and it is up to the bacteria to degrade the remaining contamination.Learn More
How to Cite MetaCyc
Please cite MetaCyc as Caspi et al 2020, "The MetaCyc database of metabolic pathways and enzymes - a 2019 update", Nucleic Acids Research 48(D1):D445-D453
The development of MetaCyc is funded by grant GM080746 from the NIH National Institute of General Medical Sciences.
- BioCyc site contents, including EcoCyc, MetaCyc, and our extensive database collection
- How to search, browse, and find what you need in the BioCyc collection
- How we represent metabolism, transcription, and all their parts
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