MetaCyc phenylalkylamine N-methyltransferase

gene

enzyme

Accession IDs	G-80786 (MetaCyc) A0A2Z3EKZ6 (UniProt)
Reactions	2.1.1.M76: (1R,2S)-ephedrine + S-adenosyl-L-methionine → (1R,2S)-N-methylephedrine + S-adenosyl-L-homocysteine + H⁺ 2.1.1.M76: (1S,2S)-pseudoephedrine + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + (+)-(1S,2S)-N-methylpseudoephedrine + H⁺ 2.1.1.M76: (S)-cathinone + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + (S)-N-methylcathinone + H⁺ + 2 more 2.1.1.M76: (1R,2S)-norephedrine + S-adenosyl-L-methionine → (1R,2S)-ephedrine + S-adenosyl-L-homocysteine + H⁺ 2.1.1.M76: (1S,2S)-norpseudoephedrine + S-adenosyl-L-methionine → (1S,2S)-pseudoephedrine + S-adenosyl-L-homocysteine + H⁺ [Show fewer]
Pathway	ephedrine biosynthesis
Evidence	Assay of protein purified to homogeneity from a heterologous host [Morris18]