MetaCyc fused UDP-4-amino-4-deoxy-L-arabinose formyltransferase/UDP-glucuronate dehydrogenase

gene

enzyme

Synonyms	SAF; yfbG; pmrI
Accession IDs	G7168 (MetaCyc) b2255 ECK2248 P77398 (UniProt)	Length	1983 bp / 660 aa
		Map Position	[2,368,039 -> 2,370,021]
		Locations	membrane , cytosol
Reactions	2.1.2.13: UDP-4-amino-4-deoxy-β-L-arabinopyranose + an N¹⁰-formyltetrahydrofolate → UDP-4-deoxy-4-formamido-β-L-arabinopyranose + a tetrahydrofolate + H⁺ 1.1.1.305: UDP-α-D-glucuronate + NAD⁺ → UDP-β-L-threo-pentapyranos-4-ulose + CO₂ + NADH
Pathway	polymyxin resistance
Evidence	Assay of unpurified protein [Breazeale02] Assay of partially-purified protein [Breazeale05] Assay of protein purified to homogeneity [GatzevaTopalova04, Williams05a, GatzevaTopalova05a, Polizzi12, GatzevaTopalova05]