Synonyms fabC; β-ketoacyl-ACP synthase I; β-ketoacyl-[acyl carrier protein] synthase I; KASI
Accession IDs EG10274 (MetaCyc)
b2323
ECK2317
P0A953 (UniProt)
Length 1221 bp / 406 aa
Map Position
[2,440,385 <- 2,441,605]
Location cytosol Inferred from high throughput experimentInferred from experimentInferred by computational analysis
Reactions 2.3.1.41: long-chain fatty acyl-[acyl-carrier protein] + malonyl-[acp] + H+ → long-chain 3-oxoacyl-[acp] + CO2 + acyl-carrier protein
2.3.1.41/2.3.1.179: (5Z)-dodec-5-enoyl-[acp] + malonyl-[acp] + H+ → (7Z)-3-oxotetradec-7-enoyl-[acp] + acyl-carrier protein + CO2
2.3.1.41/2.3.1.179: (7Z)-tetradec-7-enoyl-[acp] + malonyl-[acp] + H+ → (9Z)-3-oxohexadec-9-enoyl-[acp] + acyl-carrier protein + CO2
Pathways (5Z)-dodecenoate biosynthesis I
superpathway of fatty acid biosynthesis initiation
cis-vaccenate biosynthesis
Evidence
Inferred from experiment
Assay of unpurified protein [Lin, 2010]
Inferred from direct assay [Alberts, 1972, Feng, 2009]
Assay of protein purified to homogeneity from its native host [McGuire, 2001, Jackowski, 2002, Heath, 1996]
Assay of protein purified to homogeneity [von Wettstein-Knowles, 2006, Kim, 2006, Borgaro, 2011, Edwards, 1997, Garwin, 1980]