MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:

Megathyrsus maximus : pyruvate phosphate dikinase Inferred from experiment
Zea mays : pyruvate orthophosphate dikinase Inferred from experiment : pdk1

In Pathway: L-glutamine biosynthesis III , C4 photosynthetic carbon assimilation cycle, NADP-ME type , C4 photosynthetic carbon assimilation cycle, NAD-ME type , C4 photosynthetic carbon assimilation cycle, PEPCK type

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: pyruvate, phosphate dikinase

Enzyme Commission Synonyms: pyruvate, orthophosphate dikinase, pyruvate-phosphate dikinase (phosphorylating), pyruvate, phosphate dikinase, pyruvate-inorganic phosphate dikinase, pyruvate-phosphate dikinase, pyruvate-phosphate ligase, pyruvic-phosphate dikinase, pyruvic-phosphate ligase, pyruvate, Pi dikinase, PPDK

Standard Gibbs Free Energy (ΔrG in kcal/mol): -13.72406 Inferred by computational analysis [Latendresse13]

Citations: [Hatch68, Reeves68, Reeves71, Reeves68a]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R00206 , Rhea:10756

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC: , UniProt:RELATED-TO:O23404 , UniProt:RELATED-TO:O24612 , UniProt:RELATED-TO:O85840 , UniProt:RELATED-TO:P22221 , UniProt:RELATED-TO:P22983 , UniProt:RELATED-TO:P37213 , UniProt:RELATED-TO:Q7M0I6 , UniProt:RELATED-TO:Q9WYA9 , UniProt:RELATED-TO:Q39734 , UniProt:RELATED-TO:Q39735 , UniProt:RELATED-TO:Q41846 , UniProt:RELATED-TO:Q42367 , UniProt:RELATED-TO:Q42368 , UniProt:RELATED-TO:Q42736 , UniProt:RELATED-TO:Q42910


Hatch68: Hatch MD, Slack CR (1968). "A new enzyme for the interconversion of pyruvate and phosphopyruvate and its role in the C4 dicarboxylic acid pathway of photosynthesis." Biochem J 106(1);141-6. PMID: 4305612

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Reeves68: Reeves RE (1968). "A new enzyme with the glycolytic function of pyruvate kinase." J Biol Chem 243(11);3202-4. PMID: 4297474

Reeves68a: Reeves RE, Menzies RA, Hsu DS (1968). "The pyruvate-phosphate dikinase reaction. The fate of phosphate and the equilibrium." J Biol Chem 243(20);5486-91. PMID: 4302788

Reeves71: Reeves RE (1971). "Pyruvate,phosphate dikinase from Bacteroides symbiosus." Biochem J 125(2);531-9. PMID: 5144757

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Oct 6, 2015, BIOCYC14A.