Parent Class:

EC-Numbers → 5 -- Isomerases → 5.5 -- Intramolecular lyases → 5.5.1 -- Intramolecular lyases

Synonyms: 3-carboxymuconate cyclase, 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)

Systematic Name: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (ring-opening)

Unification Links: BRENDA:5.5.1.5, ENZYME:5.5.1.5, IUBMB-ExplorEnz:5.5.1.5

Reaction:
3-carboxy-2,5-dihydro-5-oxofuran-2-acetate ↔ 3-carboxy-cis,cis-muconate + H⁺

Citations: [Gross et al., 1956]

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References

Gross SR, Gafford RD, Tatum EL (1956). "The metabolism of protocatechuic acid by Neurospora." J Biol Chem 219(2);781-96. PMID: 13319299

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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