Parent Class:

EC-Numbers → 4 -- Lyases → 4.4 -- Carbon-sulfur lyases → 4.4.1 -- Carbon-sulfur lyases

Synonyms: homocysteine desulfurase, L-homocysteine hydrogen-sulfide-lyase (deaminating)

Systematic Name: L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming)

Unification Links: BRENDA:4.4.1.2, ENZYME:4.4.1.2, IUBMB-ExplorEnz:4.4.1.2

Reaction:
L-homocysteine + H₂O → hydrogen sulfide + 2-oxobutanoate + ammonium

Enzymes and Genes:
cystathionine γ-lyase: CTH ( Homo sapiens )

Summary:
A pyridoxal-phosphate protein.

Citations: [Kallio51]

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References

Kallio51: Kallio, R. E. (1951). "Function of pyridoxal phosphate in desulfhydrase systems of Proteus morganii." J Biol Chem 192(1);371-7. PMID: 14917685

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Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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