MetaCyc EC 3.2.1.74 -- glucan 1,4-β-glucosidase

Parent Class: EC-Numbers → 3 -- Hydrolases → 3.2 -- Glycosylases → 3.2.1 -- Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds

Synonyms: exo-1,4-β-glucosidase, exocellulase, exo-β-1,4-glucosidase, exo-β-1,4-glucanase, β-1,4-β-glucanase, β-glucosidase, exo-1,4-β-glucanase, 1,4-β-D-glucan glucohydrolase

Systematic Name: 4-β-D-glucan glucohydrolase

Unification Links: BRENDA:3.2.1.74, ENZYME:3.2.1.74, IUBMB-ExplorEnz:3.2.1.74

Reaction:
(1,4-β-D-glucosyl)(n) + H2O → (1,4-β-D-glucosyl)(n-1) + D-glucopyranose

Summary:
This enzyme catalyzes the hydrolysis of (1→4)-linkages in (1→4)-β-D-glucans, to remove successive glucose units. It acts on 1,4-β-D-glucans and related oligosaccharides. Cellobiose is hydrolysed, but very slowly.

Citations: [Barras69]

References

Barras69: Barras, D.R., Moore, A.E., Stone, B.A. (1969). "Enzyme-substrate relations among β-glucan hydrolases." Adv. Chem. Ser. 95:105-138.

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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