| Parent Class: | EC-Numbers → 2 -- Transferases → 2.1 -- Transferring one-carbon groups → 2.1.1 -- Methyltransferases |
Synonyms: BsmB, DMT
Systematic Name: S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase (betaine-forming)
Unification Links: BRENDA:2.1.1.161, ENZYME:2.1.1.161, IUBMB-ExplorEnz:2.1.1.161
Reaction:
S-adenosyl-L-methionine + N,N-dimethylglycine → S-adenosyl-L-homocysteine + glycine betaine + H+
Enzymes and Genes:
sarcosine-dimethylglycine methyltransferase [multifunctional]:
AF216283 (
Actinopolyspora halophila
)
sarcosine-dimethylglycine methyltransferase [multifunctional]:
AF216282 (
Halorhodospira halochloris
)
dimethylglycine-betaine methyltransferase:
AB094498 (
Aphanothece halophytica
)
glycine/sarcosine/N,N-dimethylglycine methyltransferase (
Methanohalophilus portucalensis
)
Summary:
This enzyme, from the marine cyanobacterium Synechococcus sp. strain WH8102, differs from
EC 2.1.1.157, sarcosine/dimethylglycine N-methyltransferase in that it cannot use sarcosine as an alternative substrate
[Lu06a]. Betaine is a 'compatible solute' that enables cyanobacteria to cope with osmotic stress by maintaining a positive cellular turgor.
References
Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
Page generated by Pathway Tools version 28.5 (software by SRI International) on Sat Mar 29, 2025, BIOCYC16A.
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