Parent Class:

EC-Numbers → 1 -- Oxidoreductases → 1.4 -- Acting on the CH-NH(2) group of donors → 1.4.3 -- With oxygen as acceptor

Systematic Name: putrescine:oxygen oxidoreductase (deaminating)

Unification Links: BRENDA:1.4.3.10, ENZYME:1.4.3.10, IUBMB-ExplorEnz:1.4.3.10

Reaction:
putrescine + dioxygen + H₂O → ammonium + hydrogen peroxide + 4-aminobutanal

Enzymes and Genes:
copper-containing amine oxidase: DAO1 ( Pisum sativum )
putrescine oxidase: puo ( Kocuria rosea )
copper-containing amine oxidase: AO1 ( Arabidopsis thaliana col )

Summary:
A flavoprotein (FAD). 4-Aminobutanal condenses non-enzymically to 1-pyrroline.

Citations: [DeSa72]

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References

DeSa72: DeSa RJ (1972). "Putrescine oxidase from Micrococcus rubens. Purification and properties of the enzyme." J Biol Chem 247(17);5527-34. PMID: 4341347

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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