Parent Class:

EC-Numbers → 1 -- Oxidoreductases → 1.3 -- Acting on the CH-CH group of donors → 1.3.1 -- With NAD(+) or NADP(+) as acceptor

Systematic Name: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD⁺ oxidoreductase (decarboxylating)

Unification Links: BRENDA:1.3.1.68, ENZYME:1.3.1.68, IUBMB-ExplorEnz:1.3.1.68

Reaction:
NAD⁺ + 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate → CO₂ + NADH + 3-methylcatechol

Summary:
Involved in the o-xylene degradation pathway in bacteria.

Citations: [Higson92]

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References

Higson92: Higson FK, Focht DD (1992). "Degradation of 2-methylbenzoic acid by Pseudomonas cepacia MB2." Appl Environ Microbiol 58(1);194-200. PMID: 1371658

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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