Parent Class:

EC-Numbers → 1 -- Oxidoreductases → 1.21 -- Acting on x-H and y-H to form an x-y bond → 1.21.3 -- With oxygen as acceptor

Synonyms: sulochrin oxidase

Systematic Name: sulochrin:oxygen oxidoreductase (cyclizing, (-)-specific)

Unification Links: BRENDA:1.21.3.5, ENZYME:1.21.3.5, IUBMB-ExplorEnz:1.21.3.5

Supersedes EC number: 1.10.3.8

Reaction:
2 sulochrin + dioxygen + 2 H⁺ → 2 (-)-bisdechlorogeodin + 2 H₂O

Enzymes and Genes:
sulochrin oxidase ( Erysiphaceae )

Summary:
Also acts on several diphenols and phenylenediamines, but has low affinity for these substrates. Involved in the biosynthesis of mould metabolites related to the antibiotic griseofulvin.

Citations: [Nordlov82]

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References

Nordlov82: Nordlov H, Gatenbeck S (1982). "Enzymatic synthesis of (+)- and (-)-bisdechlorogeodin with sulochrin oxidase from Penicillium frequentans and Oospora sulphurea-ochracea." Arch Microbiol 131(3);208-11. PMID: 7049104

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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