Parent Class:

EC-Numbers → 1 -- Oxidoreductases → 1.14 -- Acting on paired donors, with incorporation or reduction of molecular oxygen → 1.14.14 -- With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

Synonyms: StyA, SMO, NSMOA

Systematic Name: styrene,FADH₂:oxygen oxidoreductase

Unification Links: BRENDA:1.14.14.11, ENZYME:1.14.14.11, IUBMB-ExplorEnz:1.14.14.11

Reaction:
styrene + FADH₂ + dioxygen → (S)-2-phenyloxirane + FAD + H⁺ + H₂O

Enzymes and Genes:
styrene monooxygenase monooxygenase component: styA ( Pseudomonas fluorescens ST )

Summary:
The enzyme is involved in the aerobic styrene degradation pathway. It forms a two-component system with a reductase (StyB) that utilizes NADH to reduce flavin-adenine dinucleotide, which is then transferred to the oxygenase.

Citations: [Otto04, Tischler10]

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References

Otto04: Otto K, Hofstetter K, Rothlisberger M, Witholt B, Schmid A (2004). "Biochemical characterization of StyAB from Pseudomonas sp. strain VLB120 as a two-component flavin-diffusible monooxygenase." J Bacteriol 186(16);5292-302. PMID: 15292130

Tischler10: Tischler D, Kermer R, Groning JA, Kaschabek SR, van Berkel WJ, Schlomann M (2010). "StyA1 and StyA2B from Rhodococcus opacus 1CP: a multifunctional styrene monooxygenase system." J Bacteriol 192(19);5220-7. PMID: 20675468

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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