Parent Class:

EC-Numbers → 1 -- Oxidoreductases → 1.12 -- Acting on hydrogen as donor → 1.12.98 -- With other, known, acceptors

Synonyms: H₂-forming N⁵,N¹⁰-methylenetetrahydromethanopterin dehydrogenase, nonmetal hydrogenase, N⁵,N¹⁰-methenyltetrahydromethanopterin hydrogenase, hydrogen:N⁵,N¹⁰-methenyltetrahydromethanopterin oxidoreductase

Systematic Name: hydrogen:5,10-methenyltetrahydromethanopterin oxidoreductase

Unification Links: BRENDA:1.12.98.2, ENZYME:1.12.98.2, IUBMB-ExplorEnz:1.12.98.2

Supersedes EC number: 1.12.99.4

Reaction:
5,10-methenyltetrahydromethanopterin + H₂ ↔ 5,10-methylene-tetrahydromethanopterin + H⁺

Enzymes and Genes:
H₂-forming methylene-H₄MPT dehydrogenase: hmd ( Methanothermobacter thermautotrophicus )

Summary:
Does not catalyse the reduction of artificial dyes by H(2). Does not by itself catalyse a H(2)/H(+) exchange reaction.

Citations: [Klein95a]

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References

Klein95a: Klein AR, Fernandez VM, Thauer RK (1995). "H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase: mechanism of H2 formation analyzed using hydrogen isotopes." FEBS Lett 1995;368(2);203-6. PMID: 7628605

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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