Parent Class:

EC-Numbers → 1 -- Oxidoreductases → 1.1 -- Acting on the CH-OH group of donors → 1.1.3 -- With oxygen as acceptor

Systematic Name: D-hexose:oxygen 1-oxidoreductase

Unification Links: BRENDA:1.1.3.5, ENZYME:1.1.3.5, IUBMB-ExplorEnz:1.1.3.5

Reaction:
D-glucopyranose + dioxygen = D-glucono-1,5-lactone + hydrogen peroxide

Unofficial Reactions:
D-mannopyranose + dioxygen → D-mannono-1,5-lactone + hydrogen peroxide,
D-galactopyranose + dioxygen → D-galactono-1,5-lactone + hydrogen peroxide

Summary:
A copper glycoprotein. Also oxidizes D-galactose, D-mannose, maltose, lactose and β-D-cellobiose.

Citations: [BeanRC56, Bean61, Sullivan73]

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References

Bean61: Bean RC, Porter GG, Steinberg BM (1961). "Carbohydrate metabolism of citrus fruits. II. Oxidation of sugars by an aerodehydrogenase from young orange fruits." J Biol Chem 236;1235-40. PMID: 13688220

BeanRC56: BeanRC, Hassid WZ (1956). "Carbohydrate oxidase from A red alga, Iridophycus flaccidum." J Biol Chem 218(1);425-36. PMID: 13278350

Sullivan73: Sullivan JD, Ikawa M (1973). "Purification and characterization of hexose oxidase from the red alga Chondrus crispus." Biochim Biophys Acta 309(1);11-22. PMID: 4708670

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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