MetaCyc Overview
MetaCyc is a database of nonredundant, experimentally elucidated metabolic pathways. MetaCyc contains
more than 1,400 pathways from more than 1,800 different
organisms
[more],
and is curated from the scientific experimental literature.
[more]
MetaCyc contains pathways involved in both primary
[def]
and secondary [def]
metabolism, as well as associated compounds, enzymes, and genes.
[more]
Motivations
The goal of MetaCyc is to catalog the universe of metabolism by storing a representative sample of each experimentally
elucidated pathway.
[MetaCyc mission]
MetaCyc is used in a variety of scientific applications, such as providing a reference data set for computationally
predicting the metabolic pathways of organisms from their sequenced genomes, supporting metabolic engineering, helping to
compare biochemical networks, and serving as an encyclopedia of metabolism.
[scientific applications]
Recent Publication
Query and Visualization
MetaCyc pathways can be browsed from a list, from ontologies
[def], or queried directly when searching for
pathways, proteins, reactions or compounds.
[more] MetaCyc can also be queried
programmatically using
Java
or
PERL when installed locally.
[more]
New Users
Get a bird's eye view of the MetaCyc web site
here.
How to Cite MetaCyc
Please cite MetaCyc as Caspi et al., 2008,
"The MetaCyc Database of metabolic pathways and enzymes and the BioCyc
collection of Pathway/Genome Databases", Nucleic Acids Research
in publications resulting from its use.
Acknowledgments
The development of MetaCyc is funded by grant
GM080746 from the NIH National Institute of General Medical Sciences.
